A cosmetic ingredient that promises to transform facial aesthetics by providing healthy rejuvenation without the use of invasive procedures.

By the year 2030, the global facial injectables market is estimated to reach the significant figure of 24.92 billion dollars, with an average annual growth rate of 12.0% from 2023 to 2030, as identified in a new report from Grand View Research, Inc. These procedures play a crucial role in anti-aging treatments, especially employed to combat damage such as hyperpigmentation and premature aging. Botox and facial fillers stand out as the most sought-after treatments in all socioeconomic strata, gaining considerable popularity. This scenario creates opportunities for the introduction of alternative products in the market.

Seeking a non-invasive alternative to injectable skin fillers, Chemyunion has developed Cellfie®, a plant-based ingredient with a precise and efficient delivery system to stimulate adipogenesis by stimulating adiponectin in a way to mitigate signs of aging.

Cellfie® can be used to replace invasive forms of facial filling, which can often result in an unnatural appearance due to filler injections into the dermis, an extremely fibrous layer of the skin composed of collagen and elastin, and naturally resistant to this type of procedure. Considering consumers’ growing concerns about the safety and discomfort associated with these skin treatments, we believe there is a significant market niche for natural products capable of offering results comparable to the invasive applications we know today.

This ingredient has a precise system for stimulating skin and wrinkle filling – non-invasively – using Thymus vulgaris (thyme) extract. Its goal is to improve structural aging due to lipoatrophy or loss of adipose tissue, promoting a remarkable rejuvenation with a natural appearance. Improved facial contour and modification are among its main benefits, making it a definitive alternative to invasive fillers available in the market.

Cellfie® acts by inducing adipogenesis through increased adiponectin expression by 122% – a key mediator in the proliferation and differentiation of adipocytes, as well as in lipid accumulation within cells. Additionally, clinical studies have shown remarkable results for wrinkle filling and natural facial contouring.

With exceptional performance in topical skin treatments, this ingredient has a precise and effective liposome delivery system that, when tested and compared with the benchmark, stimulates adiponectin 5x more (the main biological marker responsible for adipogenesis regulation), thus restoring cellular memory and consequently resulting in natural and remarkable skin rejuvenation.

Benefits

Cellfie® acts by:

• Stimulating skin filling through adipogenesis induction – promoted by adiponectin and PPAR expression.
• Improving and modifying facial contour through filling stimulation, being a definitive alternative to invasive fillers available in the market.
• Improving lip volume with visible results in as little as 7 days.

Efficacy Tests:

1.         Adipogenesis Induction

Figure 1: Evaluation of Cellfie® effects on adipogenesis induction in pre-adipocyte culture. Increased by 40 times.

2.         Clinical Test

a.         Facial Filling

Figure 2: Effect of Cellfie® on perioral, orbital, smile lines, and nasolabial wrinkles after 60 days of treatment.

b.         Lip Volumization

Figure 3: Efficacy of Cellfie® in improving lip volume in just 7 days of treatment.

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